Browsing by Author "Tung, Kang"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Panax ginseng and salvia miltiorrhiza supplementation abolishes eccentric exercise-induced vascular stiffening: a double-blind randomized control trial
    (2016-06-06) Lin, Hsin-Fu; Tung, Kang; Chou, Chun-Chung; Lin, Ching-Che; Lin, Jaung-Geng; Tanaka, Hirofumi
    Abstract Background Muscle damage induced by unaccustomed or eccentric exercise results in delayed onset vascular stiffening. We tested the hypothesis that a 7-day supplementation of panax ginseng and salvia miltiorrhiza prior to an acute eccentric exercise could attenuate arterial stiffening. Methods By using a double-blind study placebo-controlled randomized design, subjects were randomly assigned to either the Chinese herb (N = 12) or the placebo group (N = 11) and performed a downhill running (eccentric exercise) trial and a control (seated rest) trial. Results Muscle soreness increased 1–2 days after exercise similarly in both groups, whereas the herb group demonstrated a faster recovery on active range of motion. Plasma creatine kinase concentration increased significantly at 24 h in both groups but the magnitude of increase was attenuated in the herb group. Arterial stiffness as measured by carotid-femoral pulse wave velocity increased significantly at 24 h in the placebo group but such increase was absent in the herb group. Flow-mediated dilation did not change in either group. Plasma concentrations of CRP and IL-6 increased in the placebo group but no such increases were observed in the herb group. Changes in arterial stiffness induced by eccentric exercise were associated with the corresponding changes in IL-6 (r = 0.46, P < 0.05). Conclusions A short-term Chinese herb supplementation of panax ginseng and salvia miltiorrhiza ameliorated the delayed onset vascular stiffening induced by acute downhill running exercise. Trial registration ClinicalTrials.gov: NCT02007304. Registered Dec. 5, 2013)
  • No Thumbnail Available
    Item
    運動後增補不同劑量葡萄糖對前期高血壓至高血壓男性之踝臂脈波傳導速率及血壓的效應
    (2023) 童亢; Tung, Kang
    背景：有氧運動能改善動脈硬化指標－脈波傳導速率 (pulse wave velocity, PWV) 及血壓，而增補葡萄糖會導致高血糖使PWV及血壓上升。研究指出，正常血壓者進行有氧運動能抵消75g葡萄糖增補造成血壓及PWV的負面影響，不過，目前對於非正常血壓者及不同劑量葡萄糖增補下是否有相同效應仍有待釐清。目的：探討前期高血壓者至高血壓男性在單次有氧運動後增補不同劑量葡萄糖對踝臂脈波傳導速率 (brachial-ankle PWV, baPWV) 及血壓之效應。方法：招募12位無規律運動之前期高血壓至高血壓的成年男性並檢測65% 儲備心跳率。接著，以雙盲及平衡次序之實驗設計，在65% HRR強度跑步機運動30分鐘後立即增補0g (安慰劑；PT)、25g (25T)、75g (75T) 葡萄糖三種實驗處理，每次實驗處理間隔至少7天。baPWV、血壓及血流調節舒張功能 (flow-mediated dilation, FMD) 於運動前、運動後30、60、90及120分鐘檢測。結果：不同劑量葡萄糖處理的baPWV在運動前皆無差異 (p> .05)，75T之baPWV在運動後120分鐘顯著高於PT (p < .05)，但25T之baPWV與PT無差異。PT之baPWV在運動後60及90分鐘顯著低於運動前 (p < .05)；不同劑量葡萄糖處理的平均動脈壓 (mean arterial pressure, MAP) 在各時間點皆無差異，75T的MAP在運動前與後無差異，而25T的MAP在運動後60至120分鐘顯著低於運動前 (p < .05)，PT的MAP在運動後60及90分鐘顯著低於運動前 (p < .05)；不同劑量葡萄糖處理的FMD在運動前皆無差異 (p > .05)，但75T之FMD在運動後各時間點皆顯著低於PT及25T (p < .05)，而25T之FMD在運動後30至90分鐘顯著低於PT (p < .05)。PT之FMD在運動後各時間點皆顯著高於運動前 (p < .05)。結論：有氧運動後立即增補75g葡萄糖會造成baPWV和FMD短暫負面影響，以及抵消有氧運動後降低MAP的效益。當有氧運動後增補葡萄糖劑量降至25g能減少葡萄糖對FMD及baPWV造成的負面影響，並達到運動後降低MAP的效益。