三氯化鐵輔佐螺旋[4.6]十一-8-酮架構的合成
| dc.contributor | 葉名倉 | zh_TW |
| dc.contributor | Ming-Chang P. Yeh | en_US |
| dc.contributor.author | 邱緯航 | zh_TW |
| dc.contributor.author | Wei-Hang Chiu | en_US |
| dc.date.accessioned | 2019-09-04T10:08:50Z | |
| dc.date.available | 2017-8-6 | |
| dc.date.available | 2019-09-04T10:08:50Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | 本篇論文旨在於利用三氯化鐵輔佐帶有芳香環炔基支鏈的雙環[4.1.0]庚-2-酮化合物進行一連串的擴環、環化及氯化反應形成螺旋[4.6]十一-8-酮的架構。 反應最佳條件是將帶有各種芳香環炔基支鏈的雙環[4.1.0]庚-2-酮化合物以1,2-二溴乙烷作為溶劑，使用1.5 當量的三氯化鐵並加熱至50 ℃可得到(E)-螺旋[4.6]十一-8-酮的架構，產率24-62 %。X-ray 繞射分析證明了環化產物中的烯基為(E)-構型。 | zh_TW |
| dc.description.abstract | Construction of spiro[4.6]undecan-8-ones via iron(III) chloride-promoted tandem ring expansion/cyclization/chlorination of arylalkynyl-tethered bicyclo[4.1.0]heptan-2-ones was demonstrated. Treatment of arylalkynyl-tethered bicyclo[4.1.0]heptan-2-ones with 1.5 equivalents of iron(III) chloride in 1,2-dibromoethane at 50 ℃ afforded spiro[4.6]undecan-8-ones in 24-62 % yield. Structure elucidation of the (E)-form products was achieved by X-ray crystallography. | en_US |
| dc.description.sponsorship | 化學系 | zh_TW |
| dc.identifier | GN0699420015 | |
| dc.identifier.uri | http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN0699420015%22.&%22.id.& | |
| dc.identifier.uri | http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100914 | |
| dc.language | 中文 | |
| dc.subject | 三氯化鐵 | zh_TW |
| dc.subject | 擴環 | zh_TW |
| dc.subject | 環化 | zh_TW |
| dc.subject | 螺旋 | zh_TW |
| dc.subject | iron trichloride | en_US |
| dc.subject | ring expansion | en_US |
| dc.subject | cyclization | en_US |
| dc.subject | spiro | en_US |
| dc.title | 三氯化鐵輔佐螺旋[4.6]十一-8-酮架構的合成 | zh_TW |
| dc.title | Iron Trichloride-Promoted Construction of Spiro[4.6]undecan-8-ones | en_US |
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